Journal · What we're learning
Formulation science, regulatory changes, and the unglamorous decisions that decide whether a product works.
EVIDENCE
A new study found real improvements in memory, physical performance and stress from placebo pills, even when people knew the pills were fake. Most supplements are dosed too low to clear that baseline.
PRODUCT DEVELOPMENT
A manufacturer will quote and build exactly what you hand them, including a formula whose hero ingredient isn't TGA-permitted, or whose dose doesn't match the evidence you plan to cite. Formulating first is what makes everything downstream straightforward.
EVIDENCE
An ingredient can be studied at 600mg and included in a product at 50mg. The claim still stands; the efficacy almost certainly doesn't. Under the TGA's listed medicine framework, permitted indications must be substantiated, but nothing forces the dose on the label to match the dose in the literature.
FORMULATION SCIENCE
Magnesium oxide absorbs at rates as low as 4%; B12 as cyanocobalamin needs a conversion some people cannot efficiently make. Same mineral, same vitamin on the label, yet the form, the delivery system and the excipient matrix decide whether any of it reaches the bloodstream.
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